Standard
Congenital heart malformation
MAML3 · rs1531070
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Congenital heart malformation compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Congenital heart malformation.
G/G
Published research associates this genotype with typical/baseline likelihood of Congenital heart malformation — no copies of the reported risk allele.
Source
A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations
Hu Z,
Shi Y,
Mo X,
Xu J,
Zhao B,
Lin Y,
Yang S,
Xu Z,
Dai J,
Pan S,
Da M,
Wang X
and 15 more — show all
Qian B,
Wen Y,
Wen J,
Xing J,
Guo X,
Xia Y,
Ma H,
Jin G,
Yu S,
Liu J,
Zhou Z,
Wang X,
Chen Y,
Sha J,
Shen H
Nature genetics · 2013 · PMID 23708190
Questions about rs1531070
What is rs1531070?
rs1531070 is a single position in the genome, in or near the MAML3 gene. Published research associates it with congenital heart malformation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1531070 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1531070 come from?
GWAS Catalog, Nat Genet 2013, PMID:23708190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants