Sensitive

Venous thromboembolism

MAP3K2 · rs1518760

Where this position leads

Condition: Venous Thromboembolism

rs1518760 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs1518760 rs1518760 MAP3K2

What the study found

Who was studied 71,771 European ancestry cases, 7,482 African ancestry cases, 189 South Asian ancestry cases, 507 East Asian ancestry cases, 1,720 Hispanic cases, 1,426,717 controls.

The effect Each copy of the T allele shifted the measure 0.0702 lower (95% confidence interval 0.059-0.082); p = 6 × 10−33.

How common The T allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 2, band 2q14.3 — in an intron of MAP3K2.

What each result means

G/G No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1518760

What is rs1518760?

rs1518760 is a single position in the genome, in or near the MAP3K2 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1518760 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs1518760 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1518760 come from?

GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism (rs1518760). MyGeneLog™. https://www.mygenelog.com/variants/rs1518760

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