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LPO protein levels

near IL20 · rs1518108

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0408 higher (95% confidence interval 0.03-0.052); p = 4 × 10−15.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — between genes, 0.6 kb from IL20.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of LPO protein levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with LPO protein levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of LPO protein levels compared to the general population.
Source

Questions about rs1518108

What is rs1518108?

rs1518108 is a single position in the genome, in or near the near IL20 gene. Published research associates it with lpo protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1518108 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1518108 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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LPO protein levels (rs1518108). MyGeneLog™. https://www.mygenelog.com/variants/rs1518108

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