Standard

Degree of unsaturation

near DRP2 · rs150987536

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the G allele shifted the measure 0.01 degree higher (95% confidence interval 0.01-0.01); p = 1 × 10⁻¹⁰.

Where it sits Chromosome X, band Xq22.1 — between genes, 7.3 kb from YWHAQP8.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Degree of unsaturation — no copies of the reported risk allele.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Degree of unsaturation.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Degree of unsaturation compared to the general population.

Source

A genetic map of human metabolism across the allele frequency spectrum

Zoodsma M, Beuchel C, Yasmeen S, Kohleick L, Nepal A, Koprulu M, Kronenberg F, Mayr M, Williamson A, Pietzner M, Langenberg C

Nature genetics · 2025 · PMID 41044249 · open access

Questions about rs150987536

What is rs150987536?

rs150987536 is a single position in the genome, in or near the near DRP2 gene. Published research associates it with degree of unsaturation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150987536 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs150987536 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150987536 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Degree of unsaturation (rs150987536). MyGeneLog™. https://www.mygenelog.com/variants/rs150987536

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