Sensitive

Schizophrenia

LOC10013084 · rs1509378

Where this position leads

Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk)

rs1509378 Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk) Autism Spectrum Disorder and Schizo… Condition rs1509378 rs1509378 LOC10013084

What the study found

Who was studied 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls.

The effect Each copy of the A allele carried 1.07 times the odds of Schizophrenia (95% confidence interval 1.05-1.1); p = 5 × 10−9.

Where it sits Chromosome 2, band 2p24.1 — in an intron of LINC01830.

What each result means

A/A Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs1509378

What is rs1509378?

rs1509378 is a single position in the genome, in or near the LOC10013084 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1509378 linked to?

On MyGeneLog this position is linked to Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk). The research behind each link, and its sources, are set out on that condition page.

Does having rs1509378 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1509378 come from?

GWAS Catalog, Schizophrenia bulletin 2019, PMID:30285260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs1509378). MyGeneLog™. https://www.mygenelog.com/variants/rs1509378

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