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Proinsulin levels (late-phase conversion)

TBC1D30 · rs150781447

What the study found

Who was studied up to 8,229 Finnish ancestry non-diabetic individuals.

The effect Each copy of the T allele shifted the measure 0.204 higher (95% confidence interval 0.15-0.25); p = 1 × 10−16.

How common The T allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 12, band 12q14.3 — a missense change in TBC1D30.

What each result means

C/C No copy of the version the research linked to Proinsulin levels (late-phase conversion). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Proinsulin levels (late-phase conversion). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Proinsulin levels (late-phase conversion). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150781447

What is rs150781447?

rs150781447 is a single position in the genome, in or near the TBC1D30 gene. Published research associates it with proinsulin levels (late-phase conversion). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150781447 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150781447 come from?

GWAS Catalog, Nature genetics 2013, PMID:23263489. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Proinsulin levels (late-phase conversion) (rs150781447). MyGeneLog™. https://www.mygenelog.com/variants/rs150781447

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