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Alpha-2,8-sialyltransferase 8F levels

ST8SIA6 · rs150777747

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.03 higher (95% confidence interval 0.71-1.34); p = 3 × 10−10.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 10, band 10p12.33 — a missense change in ST8SIA6.

What each result means

A/A Two copies of the version the research linked to Alpha-2,8-sialyltransferase 8F levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Alpha-2,8-sialyltransferase 8F levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Alpha-2,8-sialyltransferase 8F levels. This is the starting point the study compared everyone against.
Source

Questions about rs150777747

What is rs150777747?

rs150777747 is a single position in the genome, in or near the ST8SIA6 gene. Published research associates it with alpha-2,8-sialyltransferase 8f levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150777747 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150777747 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alpha-2,8-sialyltransferase 8F levels (rs150777747). MyGeneLog™. https://www.mygenelog.com/variants/rs150777747

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