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Hirsutism

CFAP299 · rs150735020

Where this position leads

Condition: Hirsutism

rs150735020 Condition: Hirsutism Hirsutism Condition rs150735020 rs150735020 CFAP299

What the study found

Who was studied 502 Finnish ancestry female cases, 219,249 Finnish ancestry female controls.

The effect Each copy of the A allele carried 5.75 times the odds of Hirsutism (95% confidence interval 3.47-9.51); p = 1 × 10−11.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — in an intron of CFAP299.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hirsutism compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hirsutism.
G/G Published research associates this genotype with typical/baseline likelihood of Hirsutism — no copies of the reported risk allele.
Source
Hirsutism beyond PCOS: Genome-wide evidence for genetic factors
Takala JH, Pujol-Gualdo N, Laisk T, Uimari O, Piltonen T, Kettunen J, Tyrmi JS
FinnGen · Estonian Biobank Research Team
The Journal of investigative dermatology · 2026 · PMID 42190866

Questions about rs150735020

What is rs150735020?

rs150735020 is a single position in the genome, in or near the CFAP299 gene. Published research associates it with hirsutism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150735020 linked to?

On MyGeneLog this position is linked to Hirsutism. The research behind each link, and its sources, are set out on that condition page.

Does having rs150735020 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150735020 come from?

GWAS Catalog, The Journal of investigative dermatology 2026, PMID:42190866. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hirsutism (rs150735020). MyGeneLog™. https://www.mygenelog.com/variants/rs150735020

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