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Body shape (principal component analysis)

DNASE1 · rs150717769

What the study found

Who was studied 8,769 African ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.58 higher; p = 4 × 10−9.

How common The A allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — in an intron of DNASE1.

What each result means

A/A Two copies of the version the research linked to Body shape (principal component analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body shape (principal component analysis). That is a smaller link than two copies.
G/G No copy of the version the research linked to Body shape (principal component analysis). This is the starting point the study compared everyone against.
Source

Questions about rs150717769

What is rs150717769?

rs150717769 is a single position in the genome, in or near the DNASE1 gene. Published research associates it with body shape (principal component analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150717769 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150717769 come from?

GWAS Catalog, Nutrition, metabolism, and cardiovascular diseases : NMCD 2022, PMID:35461751. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body shape (principal component analysis) (rs150717769). MyGeneLog™. https://www.mygenelog.com/variants/rs150717769

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