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Appendicular lean mass

near NUP155 · rs150621

What the study found

Who was studied 181,862 European ancestry elderly individuals.

The effect Each copy of the G allele shifted the measure 0.0498 lower (95% confidence interval 0.036-0.063); p = 5 × 10−12.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — between genes, 3.5 kb from NUP155.

What each result means

A/A No copy of the version the research linked to Appendicular lean mass. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Appendicular lean mass. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Appendicular lean mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150621

What is rs150621?

rs150621 is a single position in the genome, in or near the near NUP155 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150621 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150621 come from?

GWAS Catalog, American journal of human genetics 2019, PMID:31761296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Appendicular lean mass (rs150621). MyGeneLog™. https://www.mygenelog.com/variants/rs150621

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