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Free Cholesterol to Total Lipids in Very Large HDL percentage

near SRGAP2C · rs150615763

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs150615763 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs150615763 rs150615763 near SRGAP2C

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the A allele shifted the measure 0.06 % lower (95% confidence interval 0.04-0.08); p = 2 × 10−14.

Where it sits Chromosome 1, band 1p11.2 — between genes, 1.1 kb from MTIF2P1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Free Cholesterol to Total Lipids in Very Large HDL percentage compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Free Cholesterol to Total Lipids in Very Large HDL percentage.
C/C Published research associates this genotype with typical/baseline likelihood of Free Cholesterol to Total Lipids in Very Large HDL percentage — no copies of the reported risk allele.
Source

Questions about rs150615763

What is rs150615763?

rs150615763 is a single position in the genome, in or near the near SRGAP2C gene. Published research associates it with free cholesterol to total lipids in very large hdl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150615763 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs150615763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150615763 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Free Cholesterol to Total Lipids in Very Large HDL percentage (rs150615763). MyGeneLog™. https://www.mygenelog.com/variants/rs150615763

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