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Ceramide (d40:1) levels

PBX4 · rs150536132

What the study found

Who was studied 7,117 Finnish ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.263 lower (95% confidence interval 0.18-0.35); p = 7 × 10−10.

How common The T allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 19, band 19p13.11 — in an intron of PBX4.

What each result means

C/C No copy of the version the research linked to Ceramide (d40:1) levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Ceramide (d40:1) levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Ceramide (d40:1) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150536132

What is rs150536132?

rs150536132 is a single position in the genome, in or near the PBX4 gene. Published research associates it with ceramide (d40:1) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150536132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150536132 come from?

GWAS Catalog, Nature communications 2023, PMID:37907536. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ceramide (d40:1) levels (rs150536132). MyGeneLog™. https://www.mygenelog.com/variants/rs150536132

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