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Who was studied 102,215 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.186 higher (95% confidence interval 0.13-0.25); p = 2 × 10−9.
Where it sits Chromosome 3, band 3p24.2 — in an intron of THRB.
What each result means
C/CTwo copies of the version the research linked to Height (weighted GWA). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Height (weighted GWA). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Height (weighted GWA). This is the starting point the study compared everyone against.
Nature human behaviour · 2023 · PMID 37106081 · open access
Questions about rs1505289
What is rs1505289?
rs1505289 is a single position in the genome, in or near the THRB gene. Published research associates it with height (weighted gwa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1505289 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs1505289 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1505289 come from?
GWAS Catalog, Nature human behaviour 2023, PMID:37106081. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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