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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 121,543 European and South Asian ancestry individuals; replicated in up to 275,596 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−8.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 2, band 2q31.2 — a missense change in CCDC141.
What each result means
A/ATwo copies of the version the research linked to Smoking cessation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Smoking cessation. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Smoking cessation. This is the starting point the study compared everyone against.
Molecular psychiatry · 2020 · PMID 30617275 · open access
Questions about rs150493199
What is rs150493199?
rs150493199 is a single position in the genome, in or near the CCDC141 gene. Published research associates it with smoking cessation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs150493199 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs150493199 come from?
GWAS Catalog, Molecular psychiatry 2020, PMID:30617275. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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