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Who was studied 3,598 Qatari ancestry cases, 2,287 Qatari ancestry controls; replicated in 4,641 Qatari ancestry cases, 3,126 Qatari ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 6 × 10−12.
How common The C allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 12, band 12q21.33 — in an intron of ATP2B1-AS1.
What each result means
C/CTwo copies of the version the research linked to Vitamin D deficiency. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Vitamin D deficiency. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Vitamin D deficiency. This is the starting point the study compared everyone against.
International journal of molecular sciences · 2025 · PMID 41096749 · open access
Questions about rs150425221
What is rs150425221?
rs150425221 is a single position in the genome, in or near the near ATP2B1 gene. Published research associates it with vitamin d deficiency. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs150425221 linked to?
On MyGeneLog this position is linked to Vitamin D Deficiency and the GC Gene. The research behind each link, and its sources, are set out on that condition page.
Does having rs150425221 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs150425221 come from?
GWAS Catalog, International journal of molecular sciences 2025, PMID:41096749. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 141112216Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Vitamin D deficiency (rs150425221). MyGeneLog™. https://www.mygenelog.com/variants/rs150425221