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Mean corpuscular haemoglobin (UKB data field 30050)

LUC7L · rs150392104

Where this position leads

Condition: Celiac Disease

rs150392104 Condition: Celiac Disease Celiac Disease Condition rs150392104 rs150392104 LUC7L

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.068 higher (95% confidence interval 0.048-0.088); p = 3 × 10−12.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — in an intron of LUC7L.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). This is the starting point the study compared everyone against.
Source

Questions about rs150392104

What is rs150392104?

rs150392104 is a single position in the genome, in or near the LUC7L gene. Published research associates it with mean corpuscular haemoglobin (ukb data field 30050). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150392104 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs150392104 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150392104 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular haemoglobin (UKB data field 30050) (rs150392104). MyGeneLog™. https://www.mygenelog.com/variants/rs150392104

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