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Hidradenitis suppurativa

near TUBA3E · rs150315199

Where this position leads

Condition: Hidradenitis Suppurativa

rs150315199 Condition: Hidradenitis Suppurativa Hidradenitis Suppurativa Condition rs150315199 rs150315199 near TUBA3E

What the study found

Who was studied 2,864 European ancestry cases, 1,315,903 European ancestry controls, 1,077 African ancestry cases, 119,700 African ancestry controls.

The effect Each copy of the G allele carried 1.94 times the odds of Hidradenitis suppurativa (95% confidence interval 1.53-2.46); p = 4 × 10−8.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 2, band 2q21.1 — between genes, 3.5 kb from MED15P5.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Hidradenitis suppurativa — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hidradenitis suppurativa.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hidradenitis suppurativa compared to the general population.
Source
Multiomics analyses prioritize disease genes and pathways in hidradenitis suppurativa
Peacker BL, Ly L, Hwang JC, Gravel-Pucillo K, Zheng C, Wheless LE, Ferolito BR, Cho K, Gaziano JM, Pereira AC, Hartman RI
The Journal of investigative dermatology · 2026 · PMID 41548865

Questions about rs150315199

What is rs150315199?

rs150315199 is a single position in the genome, in or near the near TUBA3E gene. Published research associates it with hidradenitis suppurativa. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150315199 linked to?

On MyGeneLog this position is linked to Hidradenitis Suppurativa. The research behind each link, and its sources, are set out on that condition page.

Does having rs150315199 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150315199 come from?

GWAS Catalog, The Journal of investigative dermatology 2026, PMID:41548865. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hidradenitis suppurativa (rs150315199). MyGeneLog™. https://www.mygenelog.com/variants/rs150315199

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