Sensitive

Alzheimer's disease

MOB1A · rs150214656

Where this position leads

Condition: Alzheimer's Disease

rs150214656 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs150214656 rs150214656 MOB1A

What the study found

Who was studied 12,074 European, African, Admixed American, Asian or unknown ancestry cases, 15,833 European, African, Admixed American, Asian or unknown ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−8.

Where it sits Chromosome 2, band 2p13.1 — in an intron of MOB1A.

What each result means

A/A No copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150214656

What is rs150214656?

rs150214656 is a single position in the genome, in or near the MOB1A gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150214656 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs150214656 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150214656 come from?

GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2025, PMID:39998322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease (rs150214656). MyGeneLog™. https://www.mygenelog.com/variants/rs150214656

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