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CEACAM21 protein levels

near CEACAM6 · rs150127461

Where this position leads

Condition: Celiac Disease

rs150127461 Condition: Celiac Disease Celiac Disease Condition rs150127461 rs150127461 near CEACAM6

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.449 higher (95% confidence interval 0.31-0.59); p = 2 × 10−12.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 19, band 19q13.2 — between genes, 9.2 kb from CEACAM6.

What each result means

A/A No copy of the version the research linked to CEACAM21 protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to CEACAM21 protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to CEACAM21 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150127461

What is rs150127461?

rs150127461 is a single position in the genome, in or near the near CEACAM6 gene. Published research associates it with ceacam21 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150127461 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs150127461 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150127461 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CEACAM21 protein levels (rs150127461). MyGeneLog™. https://www.mygenelog.com/variants/rs150127461

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