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Interleukin-27 levels

ANKRD24 · rs150106684

What the study found

Who was studied 21,758 European ancestry individuals; replicated in 9,173 individuals.

The effect Each copy of the C allele shifted the measure 0.263 higher; p = 2 × 10−14.

How common The C allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 19, band 19p13.3 — a missense change in ANKRD24.

What each result means

C/C Two copies of the version the research linked to Interleukin-27 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Interleukin-27 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Interleukin-27 levels. This is the starting point the study compared everyone against.
Source

Questions about rs150106684

What is rs150106684?

rs150106684 is a single position in the genome, in or near the ANKRD24 gene. Published research associates it with interleukin-27 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150106684 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150106684 come from?

GWAS Catalog, Nature metabolism 2020, PMID:33067605. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Interleukin-27 levels (rs150106684). MyGeneLog™. https://www.mygenelog.com/variants/rs150106684

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