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Hashimoto thyroiditis

PPT2-EGFL8 · rs150084830

Where this position leads

Condition: Lymphocytic Thyroiditis (Hashimoto's)

rs150084830 Condition: Lymphocytic Thyroiditis (Hashimoto's) Lymphocytic Thyroiditis (Hashimoto's) Condition rs150084830 rs150084830 PPT2-EGFL8

What the study found

Who was studied 42,490 European ancestry cases, 773,420 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.274 log odds ratio lower (95% confidence interval 0.19-0.35); p = 3 × 10−11.

What each result means

C/C No copy of the version the research linked to Hashimoto thyroiditis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hashimoto thyroiditis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hashimoto thyroiditis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs150084830

What is rs150084830?

rs150084830 is a single position in the genome, in or near the PPT2-EGFL8 gene. Published research associates it with hashimoto thyroiditis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150084830 linked to?

On MyGeneLog this position is linked to Lymphocytic Thyroiditis (Hashimoto's). The research behind each link, and its sources, are set out on that condition page.

Does having rs150084830 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150084830 come from?

GWAS Catalog, Nature genetics 2026, PMID:42527560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hashimoto thyroiditis (rs150084830). MyGeneLog™. https://www.mygenelog.com/variants/rs150084830

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