Sensitive

Ischemic stroke

near RNU6-229P · rs150022429

What the study found

Who was studied 4,307 European ancestry cases, 17,021 European ancestry controls, 884 African American or Afro-Caribbean cases, 6,855 African American or Afro-Caribbean controls, 316 Hispanic or Latin American cases, 2,256 Hispanic or Latin American controls, 80 Asian ancestry cases, 734 Asian ancestry controls, 12 Native American ancestry cases, 34 Native American ancestry controls, 17 cases, 216 controls; replicated in 16,851 European, African American or Afro-Caribbean, Hispanic or Latin American cases, Asian, Native American and unknown ancestry cases, 32,473 European, African American or Afro-Caribbean, Hispanic or Latin American cases, Asian, Native American and unknown ancestry controls.

The effect Each copy of the C allele carried 5.28 times the odds of Ischemic stroke (95% confidence interval 2.90712739161519-9.580564951053887); p = 5 × 10−8.

Where it sits Chromosome 7, band 7q11.22 — between genes, 0.3 kb from RNU6-229P.

What each result means

C/C Two copies of the version the research linked to Ischemic stroke. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Ischemic stroke. That is a smaller link than two copies.
T/T No copy of the version the research linked to Ischemic stroke. This is the starting point the study compared everyone against.
Source

Questions about rs150022429

What is rs150022429?

rs150022429 is a single position in the genome, in or near the near RNU6-229P gene. Published research associates it with ischemic stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150022429 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150022429 come from?

GWAS Catalog, Stroke 2022, PMID:34727735. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ischemic stroke (rs150022429). MyGeneLog™. https://www.mygenelog.com/variants/rs150022429

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