Standard

Gut microbiota (bacterial taxa, hurdle binary method)

RAPGEF1 · rs150018970

Where this position leads

Condition: Gut Microbiota

rs150018970 Condition: Gut Microbiota Gut Microbiota Condition rs150018970 rs150018970 RAPGEF1

What the study found

Who was studied 2,223 European ancestry individuals; replicated in 1,667 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 2.2 lower (95% confidence interval 1.63-2.78); p = 7 × 10−14.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 9, band 9q34.13 — between genes, 9 kb from EIF4A1P3.

What each result means

A/A Two copies of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). That is a smaller link than two copies.
G/G No copy of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). This is the starting point the study compared everyone against.
Source

Questions about rs150018970

What is rs150018970?

rs150018970 is a single position in the genome, in or near the RAPGEF1 gene. Published research associates it with gut microbiota (bacterial taxa, hurdle binary method). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs150018970 linked to?

On MyGeneLog this position is linked to Gut Microbiota. The research behind each link, and its sources, are set out on that condition page.

Does having rs150018970 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150018970 come from?

GWAS Catalog, Nature microbiology 2020, PMID:32572223. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gut microbiota (bacterial taxa, hurdle binary method) (rs150018970). MyGeneLog™. https://www.mygenelog.com/variants/rs150018970

← See all variants