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Thyroid stimulating hormone levels

FHOD1 · rs150016766

What the study found

Who was studied 482,873 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.063 higher (95% confidence interval 0.047-0.079); p = 4 × 10−16.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 16, band 16q22.1 — in an intron of FHOD1.

What each result means

A/A Two copies of the version the research linked to Thyroid stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Thyroid stimulating hormone levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Thyroid stimulating hormone levels. This is the starting point the study compared everyone against.
Source

Questions about rs150016766

What is rs150016766?

rs150016766 is a single position in the genome, in or near the FHOD1 gene. Published research associates it with thyroid stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs150016766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs150016766 come from?

GWAS Catalog, Nature genetics 2025, PMID:41238958. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels (rs150016766). MyGeneLog™. https://www.mygenelog.com/variants/rs150016766

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