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Rosacea symptom severity

NRXN3 · rs149851565

Where this position leads

Condition: Rosacea

rs149851565 Condition: Rosacea Rosacea Condition rs149851565 rs149851565 NRXN3

What the study found

Who was studied 73,265 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.175 lower (95% confidence interval 0.12-0.23); p = 4 × 10−9.

Where it sits Chromosome 14, band 14q31.1 — between genes, 55.7 kb from LOC105370590.

What each result means

A/A No copy of the version the research linked to Rosacea symptom severity. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Rosacea symptom severity. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Rosacea symptom severity. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs149851565

What is rs149851565?

rs149851565 is a single position in the genome, in or near the NRXN3 gene. Published research associates it with rosacea symptom severity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149851565 linked to?

On MyGeneLog this position is linked to Rosacea. The research behind each link, and its sources, are set out on that condition page.

Does having rs149851565 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149851565 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:29771307. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Rosacea symptom severity (rs149851565). MyGeneLog™. https://www.mygenelog.com/variants/rs149851565

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