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Clopidogrel active metabolite levels

near LMCD1 · rs149772317

What the study found

Who was studied 513 Amish individuals.

The effect Each copy of the A allele shifted the measure 17.1 higher; p = 6 × 10−10.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 3, band 3p25.3 — in an intron of LMCD1-AS1.

What each result means

A/A Two copies of the version the research linked to Clopidogrel active metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Clopidogrel active metabolite levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Clopidogrel active metabolite levels. This is the starting point the study compared everyone against.
Source

Questions about rs149772317

What is rs149772317?

rs149772317 is a single position in the genome, in or near the near LMCD1 gene. Published research associates it with clopidogrel active metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs149772317 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149772317 come from?

GWAS Catalog, Pharmacogenet Genomics 2017, PMID:28207573. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Clopidogrel active metabolite levels (rs149772317). MyGeneLog™. https://www.mygenelog.com/variants/rs149772317

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