G/GPublished research associates this genotype with typical/baseline likelihood of Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes — no copies of the reported risk allele. (GWAS Catalog, J Am Soc Nephrol 2019, PMID:31537649)
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes. (GWAS Catalog, J Am Soc Nephrol 2019, PMID:31537649)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes compared to the general population. (GWAS Catalog, J Am Soc Nephrol 2019, PMID:31537649)
Source: GWAS Catalog, J Am Soc Nephrol 2019, PMID:31537649
Questions about rs149641852
What is rs149641852?
rs149641852 is a single position in the genome, in or near the SNCAIP gene. Published research associates it with chronic kidney disease (end stage renal disease vs. normal egfr) in type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs149641852 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs149641852 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs149641852 come from?
GWAS Catalog, J Am Soc Nephrol 2019, PMID:31537649. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.