Standard

Pediatric obstructive sleep apnea

UBE4B · rs149622283

Where this position leads

Condition: Pediatric Obstructive Sleep Apnea

rs149622283 Condition: Pediatric Obstructive Sleep Apnea Pediatric Obstructive Sleep Apnea Condition rs149622283 rs149622283 UBE4B

What the study found

Who was studied 688 European ancestry cases, 3,165 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 4 × 10−8.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 1, band 1p36.22 — in an intron of UBE4B.

What each result means

A/A Two copies of the version the research linked to Pediatric obstructive sleep apnea. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Pediatric obstructive sleep apnea. That is a smaller link than two copies.
G/G No copy of the version the research linked to Pediatric obstructive sleep apnea. This is the starting point the study compared everyone against.
Source

Questions about rs149622283

What is rs149622283?

rs149622283 is a single position in the genome, in or near the UBE4B gene. Published research associates it with pediatric obstructive sleep apnea. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149622283 linked to?

On MyGeneLog this position is linked to Pediatric Obstructive Sleep Apnea. The research behind each link, and its sources, are set out on that condition page.

Does having rs149622283 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149622283 come from?

GWAS Catalog, Sleep 2024, PMID:35902206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pediatric obstructive sleep apnea (rs149622283). MyGeneLog™. https://www.mygenelog.com/variants/rs149622283

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