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Platelet count at delivery

ARHGEF11 · rs149515620

What the study found

Who was studied 33,553 Chinese ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.788 lower (95% confidence interval 0.6-0.98); p = 2 × 10−16.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 1, band 1q23.1 — in an intron of ARHGEF11.

What each result means

A/A No copy of the version the research linked to Platelet count at delivery. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Platelet count at delivery. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Platelet count at delivery. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs149515620

What is rs149515620?

rs149515620 is a single position in the genome, in or near the ARHGEF11 gene. Published research associates it with platelet count at delivery. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs149515620 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149515620 come from?

GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet count at delivery (rs149515620). MyGeneLog™. https://www.mygenelog.com/variants/rs149515620

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