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Mean corpuscular hemoglobin

MRPL42P2 · rs149514089

Where this position leads

Condition: Blood Cell Counts

rs149514089 Condition: Blood Cell Counts Blood Cell Counts Condition rs149514089 rs149514089 MRPL42P2

What the study found

Who was studied 172,332 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.28 higher (95% confidence interval 0.21-0.35); p = 2 × 10−13.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — between genes, 3.4 kb from MYLIP.

What each result means

C/C No copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs149514089

What is rs149514089?

rs149514089 is a single position in the genome, in or near the MRPL42P2 gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149514089 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs149514089 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149514089 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin (rs149514089). MyGeneLog™. https://www.mygenelog.com/variants/rs149514089

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