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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,748 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 6.32 z score higher; p = 3 × 10−10.
How common The C allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 5, band 5q23.1 — between genes, 0.2 kb from RPL35AP15.
What each result means
C/CTwo copies of the version the research linked to Vertex-wise cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Vertex-wise cortical thickness. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Vertex-wise cortical thickness. This is the starting point the study compared everyone against.
Science advances · 2021 · PMID 34910505 · open access
Questions about rs1494828
What is rs1494828?
rs1494828 is a single position in the genome, in or near the near RPL35AP15 gene. Published research associates it with vertex-wise cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1494828 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1494828 come from?
GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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