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Natural cytotoxicity triggering receptor 1 (analyte X8360.169) levels

NCR1 · rs149458145

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.369 higher (95% confidence interval 0.26-0.48); p = 7 × 10−11.

How common The T allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 19, band 19q13.42 — in an intron of NCR1.

What each result means

C/C No copy of the version the research linked to Natural cytotoxicity triggering receptor 1 (analyte X8360.169) levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Natural cytotoxicity triggering receptor 1 (analyte X8360.169) levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Natural cytotoxicity triggering receptor 1 (analyte X8360.169) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs149458145

What is rs149458145?

rs149458145 is a single position in the genome, in or near the NCR1 gene. Published research associates it with natural cytotoxicity triggering receptor 1 (analyte x8360.169) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs149458145 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149458145 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Natural cytotoxicity triggering receptor 1 (analyte X8360.169) levels (rs149458145). MyGeneLog™. https://www.mygenelog.com/variants/rs149458145

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