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Cholesterol to Total Lipids in Medium HDL percentage

RBM6 · rs149445151

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs149445151 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs149445151 rs149445151 RBM6

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the A allele shifted the measure 0.02 % lower (95% confidence interval 0.02-0.02); p = 2 × 10−20.

Where it sits Chromosome 3, band 3p21.31 — in an intron of RBM6.

What each result means

A/A Two copies of the version the research linked to Cholesterol to Total Lipids in Medium HDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cholesterol to Total Lipids in Medium HDL percentage. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cholesterol to Total Lipids in Medium HDL percentage. This is the starting point the study compared everyone against.
Source

Questions about rs149445151

What is rs149445151?

rs149445151 is a single position in the genome, in or near the RBM6 gene. Published research associates it with cholesterol to total lipids in medium hdl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149445151 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs149445151 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149445151 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesterol to Total Lipids in Medium HDL percentage (rs149445151). MyGeneLog™. https://www.mygenelog.com/variants/rs149445151

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