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Advanced glycosylation end product-specific receptor, soluble levels

near MUC22 · rs149405105

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.47 lower (95% confidence interval 0.34-0.6); p = 1 × 10−12.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 1.9 kb from MUC22.

What each result means

A/A Two copies of the version the research linked to Advanced glycosylation end product-specific receptor, soluble levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Advanced glycosylation end product-specific receptor, soluble levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Advanced glycosylation end product-specific receptor, soluble levels. This is the starting point the study compared everyone against.
Source

Questions about rs149405105

What is rs149405105?

rs149405105 is a single position in the genome, in or near the near MUC22 gene. Published research associates it with advanced glycosylation end product-specific receptor, soluble levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs149405105 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149405105 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Advanced glycosylation end product-specific receptor, soluble levels (rs149405105). MyGeneLog™. https://www.mygenelog.com/variants/rs149405105

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