Sensitive

Depression

CCDC170 · rs149389640

Where this position leads

Condition: Endometriosis and Depression: Shared Genetics

rs149389640 Condition: Endometriosis and Depression: Shared Genetics Endometriosis and Depression: Share… Condition rs149389640 rs149389640 CCDC170

What the study found

Who was studied 688,809 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 6.17 z score higher; p = 7 × 10−10.

Where it sits Chromosome 6, band 6q25.1 — in an intron of CCDC170.

What each result means

A/A Two copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Depression. That is a smaller link than two copies.
C/C No copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
Source

Questions about rs149389640

What is rs149389640?

rs149389640 is a single position in the genome, in or near the CCDC170 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs149389640 linked to?

On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.

Does having rs149389640 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs149389640 come from?

GWAS Catalog, Nature genetics 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Depression (rs149389640). MyGeneLog™. https://www.mygenelog.com/variants/rs149389640

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