0 402226222121Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others21Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 18,942 European ancestry cases, 501,638 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.128 higher (95% confidence interval 0.085-0.172); p = 8 × 10−9.
How common The A allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 1, band 1p12 — in an intron of NOTCH2.
What each result means
A/ATwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
rs1493696 is a single position in the genome, in or near the NOTCH2 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1493696 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs1493696 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1493696 come from?
GWAS Catalog, Nature 2021, PMID:34012112. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 402226222121Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others21Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs1493696). MyGeneLog™. https://www.mygenelog.com/variants/rs1493696