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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,361 European ancestry cases, 28,384 European ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 7 × 10−14.
How common The C allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 2, band 2q37.1 — between genes, 3.7 kb from UGT1A8.
What each result means
A/ANo copy of the version the research linked to Neonatal jaundice (paternal effect). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Neonatal jaundice (paternal effect). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Neonatal jaundice (paternal effect). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39214992 · open access
Questions about rs149247216
What is rs149247216?
rs149247216 is a single position in the genome, in or near the near UGT1A8 gene. Published research associates it with neonatal jaundice (paternal effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs149247216 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs149247216 come from?
GWAS Catalog, Nature communications 2024, PMID:39214992. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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