The effect
Each copy of the G allele carried 4.90 times the odds of Diarrhoea in darapladib-treated cardiovascular disease (time to event) (95% confidence interval 2.86-8.33); p = 5 × 10−9.
How common The G allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 6, band 6q22.32 — between genes, 4.6 kb from TRMT11.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Diarrhoea in darapladib-treated cardiovascular disease (time to event) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diarrhoea in darapladib-treated cardiovascular disease (time to event).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diarrhoea in darapladib-treated cardiovascular disease (time to event) compared to the general population.
rs149232047 is a single position in the genome, in or near the near CENPW gene. Published research associates it with diarrhoea in darapladib-treated cardiovascular disease (time to event). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs149232047 linked to?
On MyGeneLog this position is linked to Darapladib Response in Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs149232047 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs149232047 come from?
GWAS Catalog, PLoS One 2017, PMID:28753643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.