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Tuberculosis

C6orf47 · rs148844907

Where this position leads

Condition: Tuberculosis

rs148844907 Condition: Tuberculosis Tuberculosis Condition rs148844907 rs148844907 C6orf47

What the study found

Who was studied 4,426 European ancestry cases, 84,290 European ancestry controls.

The effect Each copy of the A allele carried 1.92 times the odds of Tuberculosis (95% confidence interval 1.74-2.12); p = 2 × 10−12.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in the 5′ untranslated region of C6orf47.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Tuberculosis compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Tuberculosis.
T/T Published research associates this genotype with typical/baseline likelihood of Tuberculosis — no copies of the reported risk allele.
Source

Questions about rs148844907

What is rs148844907?

rs148844907 is a single position in the genome, in or near the C6orf47 gene. Published research associates it with tuberculosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs148844907 linked to?

On MyGeneLog this position is linked to Tuberculosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs148844907 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs148844907 come from?

GWAS Catalog, Nat Commun 2017, PMID:28928442. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Tuberculosis (rs148844907). MyGeneLog™. https://www.mygenelog.com/variants/rs148844907

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