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Triglycerides to Total Lipids in Medium LDL percentage

WFDC9 · rs1487326

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs1487326 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs1487326 rs1487326 WFDC9

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the C allele shifted the measure 0.01 % lower (95% confidence interval 0.01-0.01); p = 1 × 10−10.

Where it sits Chromosome 20, band 20q13.12 — in an intron of WFDC9.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides to Total Lipids in Medium LDL percentage compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides to Total Lipids in Medium LDL percentage.
T/T Published research associates this genotype with typical/baseline likelihood of Triglycerides to Total Lipids in Medium LDL percentage — no copies of the reported risk allele.
Source

Questions about rs1487326

What is rs1487326?

rs1487326 is a single position in the genome, in or near the WFDC9 gene. Published research associates it with triglycerides to total lipids in medium ldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1487326 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs1487326 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1487326 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides to Total Lipids in Medium LDL percentage (rs1487326). MyGeneLog™. https://www.mygenelog.com/variants/rs1487326

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