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GSTT2B protein levels

near GSTTP2 · rs148435972

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.205 higher (95% confidence interval 0.17-0.24); p = 4 × 10−39.

How common The G allele had a frequency of about 98% in the people studied.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of GSTT2B protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with GSTT2B protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of GSTT2B protein levels compared to the general population.
Source

Questions about rs148435972

What is rs148435972?

rs148435972 is a single position in the genome, in or near the near GSTTP2 gene. Published research associates it with gstt2b protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs148435972 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs148435972 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

GSTT2B protein levels (rs148435972). MyGeneLog™. https://www.mygenelog.com/variants/rs148435972

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