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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.
The effect
Each copy of the T allele shifted the measure 0.02 mmol/L higher (95% confidence interval 0.02-0.02); p = 4 × 10−11.
Where it sits Chromosome 6, band 6p21.1 — between genes, 17 kb from ABCC10.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Pyruvate levels — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pyruvate levels.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pyruvate levels compared to the general population.
Nature genetics · 2025 · PMID 41044249 · open access
Questions about rs148387942
What is rs148387942?
rs148387942 is a single position in the genome, in or near the near ABCC10 gene. Published research associates it with pyruvate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs148387942 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs148387942 come from?
GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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