Standard

Serum levels of protein ANKRD27

TCF7L2 · rs148288814

What the study found

Who was studied 5,358 Icelandic ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.17 higher (95% confidence interval 0.13-0.21); p = 1 × 10−15.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 10, band 10q25.2 — in an intron of TCF7L2.

What each result means

C/C No copy of the version the research linked to Serum levels of protein ANKRD27. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Serum levels of protein ANKRD27. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Serum levels of protein ANKRD27. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs148288814

What is rs148288814?

rs148288814 is a single position in the genome, in or near the TCF7L2 gene. Published research associates it with serum levels of protein ankrd27. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs148288814 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs148288814 come from?

GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum levels of protein ANKRD27 (rs148288814). MyGeneLog™. https://www.mygenelog.com/variants/rs148288814

← See all variants