Sensitive

Endometrial cancer

near IFITM3P9 · rs148261157

Where this position leads

Condition: Endometrial Cancer

rs148261157 Condition: Endometrial Cancer Endometrial Cancer Condition rs148261157 rs148261157 near IFITM3P9

What the study found

Who was studied 1,200 East Asian ancestry female cases, 60,614 East Asian ancestry female controls, 16,078 European ancestry female cases, 228,566 European ancestry female controls; replicated in 718 European ancestry female cases, 1,206 European ancestry female controls, 100 Central Asian ancestry female cases, 489 Central Asian ancestry female controls, 22 Asian ancestry female cases, 9 Asian ancestry female controls.

The effect Each copy of the A allele carried 1.27 times the odds of Endometrial cancer (95% confidence interval 1.18-1.36); p = 3 × 10−11.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 2, band 2p16.1 — between genes, 12.4 kb from IFITM3P9.

What each result means

A/A Two copies of the version the research linked to Endometrial cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Endometrial cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Endometrial cancer. This is the starting point the study compared everyone against.
Source

Questions about rs148261157

What is rs148261157?

rs148261157 is a single position in the genome, in or near the near IFITM3P9 gene. Published research associates it with endometrial cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs148261157 linked to?

On MyGeneLog this position is linked to Endometrial Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs148261157 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs148261157 come from?

GWAS Catalog, EBioMedicine 2025, PMID:40633141. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Endometrial cancer (rs148261157). MyGeneLog™. https://www.mygenelog.com/variants/rs148261157

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