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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 37,589 British ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.05 higher (95% confidence interval 0.03-0.07); p = 3 × 10−8.
How common The T allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 8, band 8p12 — in an intron of NRG1.
What each result means
C/CNo copy of the version the research linked to Paraspinal proton density fat fraction. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Paraspinal proton density fat fraction. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Paraspinal proton density fat fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of obesity · 2025 · PMID 40922984 · open access
Questions about rs1481758
What is rs1481758?
rs1481758 is a single position in the genome, in or near the NRG1 gene. Published research associates it with paraspinal proton density fat fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1481758 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1481758 come from?
GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Paraspinal proton density fat fraction (rs1481758). MyGeneLog™. https://www.mygenelog.com/variants/rs1481758