Standard

Ulcerative colitis

IL23R · rs148170789

Where this position leads

Condition: Ulcerative Colitis

rs148170789 Condition: Ulcerative Colitis Ulcerative Colitis Condition rs148170789 rs148170789 IL23R

What the study found

Who was studied 9,207 European ancestry cases, 953,183 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.384 higher (95% confidence interval 0.3-0.47); p = 1 × 10−17.

How common The A allele had a frequency of about 95% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in an intron of IL23R.

What each result means

A/A Two copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/G No copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Source

Questions about rs148170789

What is rs148170789?

rs148170789 is a single position in the genome, in or near the IL23R gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs148170789 linked to?

On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs148170789 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs148170789 come from?

GWAS Catalog, Life (Basel, Switzerland) 2026, PMID:42355477. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ulcerative colitis (rs148170789). MyGeneLog™. https://www.mygenelog.com/variants/rs148170789

← See all variants