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Who was studied 270,059 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0103 higher (95% confidence interval 0.007-0.0136); p = 1 × 10−9.
Where it sits Chromosome 13, band 13q21.32 — in an intron of PCDH9.
What each result means
A/ANo copy of the version the research linked to General factor of neuroticism. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to General factor of neuroticism. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to General factor of neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Molecular psychiatry · 2020 · PMID 30867560 · open access
Questions about rs147861665
What is rs147861665?
rs147861665 is a single position in the genome, in or near the PCDH9 gene. Published research associates it with general factor of neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs147861665 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Does having rs147861665 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs147861665 come from?
GWAS Catalog, Molecular psychiatry 2020, PMID:30867560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
General factor of neuroticism (rs147861665). MyGeneLog™. https://www.mygenelog.com/variants/rs147861665