Gene Knowledge Graph
UTC
Standard

Shingles

LRRC32 · rs147482218

Where this position leads

Condition: Shingles

rs147482218 Condition: Shingles Shingles Condition rs147482218 rs147482218 LRRC32

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Shingles compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Shingles.
T/T Published research associates this genotype with typical/baseline likelihood of Shingles — no copies of the reported risk allele.
Source
The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype
Stanaway IB, Hall TO, Rosenthal EA, Palmer M, Naranbhai V, Knevel R, Namjou-Khales B, Carroll RJ, Kiryluk K, Gordon AS, Linder J, Howell KM
and 28 more — show all
Mapes BM, Lin FTJ, Joo YY, Hayes MG, Gharavi AG, Pendergrass SA, Ritchie MD, de Andrade M, Croteau-Chonka DC, Raychaudhuri S, Weiss ST, Lebo M, Amr SS, Carrell D, Larson EB, Chute CG, Rasmussen-Torvik LJ, Roy-Puckelwartz MJ, Sleiman P, Hakonarson H, Li R, Karlson EW, Peterson JF, Kullo IJ, Chisholm R, Denny JC, Jarvik GP, Crosslin DR
eMERGE Network
Genetic epidemiology · 2019 · PMID 30298529 · open access

Questions about rs147482218

What is rs147482218?

rs147482218 is a single position in the genome, in or near the LRRC32 gene. Published research associates it with shingles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs147482218 linked to?

On MyGeneLog this position is linked to Shingles. The research behind each link, and its sources, are set out on that condition page.

Does having rs147482218 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs147482218 come from?

GWAS Catalog, Genet Epidemiol 2018, PMID:30298529. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants