Adverse response to chemotherapy (amenorrhea) in breast cancer
PPCDC · rs147451859
0 241712319Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 457 European ancestry amenorrheic cases, 711 European ancestry post-chemotherapy menses cases.
The effect
Each copy of the G allele carried 1.74 times the odds of Adverse response to chemotherapy (amenorrhea) in breast cancer; p = 6 × 10−9.
How common The G allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 15, band 15q24.2 — in an intron of PPCDC.
What each result means
C/CNo copy of the version the research linked to Adverse response to chemotherapy (amenorrhea) in breast cancer. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Adverse response to chemotherapy (amenorrhea) in breast cancer. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Adverse response to chemotherapy (amenorrhea) in breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs147451859 is a single position in the genome, in or near the PPCDC gene. Published research associates it with adverse response to chemotherapy (amenorrhea) in breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs147451859 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs147451859 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs147451859 come from?
GWAS Catalog, Fertil Steril 2019, PMID:31371054. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 241712319Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Adverse response to chemotherapy (amenorrhea) in breast cancer (rs147451859). MyGeneLog™. https://www.mygenelog.com/variants/rs147451859