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Male-pattern baldness

AUTS2 · rs1474368

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs1474368 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs1474368 rs1474368 AUTS2

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the G allele shifted the measure 0.0376 lower; p = 5 × 10−8.

Where it sits Chromosome 7, band 7q11.22 — in an intron of AUTS2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
Source

Questions about rs1474368

What is rs1474368?

rs1474368 is a single position in the genome, in or near the AUTS2 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1474368 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs1474368 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1474368 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs1474368). MyGeneLog™. https://www.mygenelog.com/variants/rs1474368

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